Ashley Deane

BSc (Hons), MSc

PhD Student

New Zealand Brain Research Institute, Christchurch

PhD Student

Department of Medicine, University of Otago, Christchurch

My PhD thesis will focus on cerebrovascular health and its relationship with cognitive impairment in Parkinson’s disease. I will use a novel MRI technique, 4D flow, to determine whether measures of cerebrovascular anatomy and haemodynamics are impaired in PD and whether they increase in severity with cognitive impairment.

Publications

Provided on request for non-commercial personal use by researchers.

2025

Download Magnetic Resonance Imaging as a Readout of CLN5 Gene Therapy Efficacy in Sheep.
Murray, S.J., Almuqbel, M.M., Felton, S.A., Palmer, N.J., Deane, A.R., Myall, D.J., Shoorangiz, R., Ella, A., Keller, M., Palmer, D.N., Melzer, T.R., Mitchell, N.L. (2025). Magnetic Resonance Imaging as a Readout of CLN5 Gene Therapy Efficacy in Sheep. Brain and Behavior, 15, e70431. 10.1002/brb3.70431
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2023

Download Cognitive and arginine metabolic correlates of temporal dysfunction in the MIA rat model of schizophrenia risk.
Deane, A., Jing, Y., Shoorangiz, R., Liu, P., Ward, R. (2023). Cognitive and arginine metabolic correlates of temporal dysfunction in the MIA rat model of schizophrenia risk. Behavioral Neuroscience, 137(1), 67–77. 10.1037/bne0000540
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2022

Download The instrumental role of operant paradigms in translational psychiatric research: Insights from a maternal immune activation model of schizophrenia risk.
Deane, A. R., Ward, R. D. (2022). The instrumental role of operant paradigms in translational psychiatric research: Insights from a maternal immune activation model of schizophrenia risk. Journal of the Experimental Analysis of Behavior, 117, 560-575. 10.1002/jeab.753
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2021

Deane, A. R., Potemkin, N., Ward, R. D. (2021). Mitogen-activated protein kinase (MAPK) signalling corresponds with distinct behavioural profiles in a rat model of maternal immune activation. Behavioural Brain Research, 396. 10.1016/j.bbr.2020.112876

2020

Niebuhr, C. N., Jarvi, S. I., Kaluna, L., Torres Fischer, B. L., Deane, A. R., Leinbach, I. L., Siers, S. R. (2020). Occurrence of rat lungworm (angiostrongylus cantonensis) in invasive coqui frogs (eleutherodactylus coqui) and other hosts in Hawaii, USA. Journal of Wildlife Diseases, 56, 203-207. 10.7589/2018-12-294
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2019

Jarvi, S. I., Jacob, J., Sugihara, R. T., Leinbach, I. L., Klasner, I. H., Kaluna, L. M., Snook, K. A., Howe, M. K., Jacquier, S. H., Lange, I., Atkinson, A. L., Deane, A. R., Niebuhr, C. N., Siers, S. R. (2019). Validation of a death assay for Angiostrongylus cantonensis larvae (L3) using propidium iodide in a rat model (Rattus norvegicus). Parasitology, 146, 1421–1428. 10.1017/S0031182019000908

2017

Deane, A. R., Millar, J., Bilkey, D. K., Ward, R. D. (2017). Maternal immune activation in rats produces temporal perception impairments in adult offspring analogous to those observed in schizophrenia. PLOS ONE, 12. 10.1371/journal.pone.0187719
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