Dr Campbell Le Heron

MBChB, FRACP, DPhil

Consultant Neurologist

Department of Neurology, Canterbury District Health Board, Christchurch

Consultant Neurologist

New Zealand Brain Research Institute, Christchurch

 

I am a Neurologist with a strong interest in cognitive disorders and the normal neural processes that underlie these deficits. I completed my undergraduate medical studies at the University of Otago, and subsequently undertook Neurology advanced training in Melbourne, Australia and a Fellowship in Oxford, UK. I was fortunate to be awarded a Christopher Welch Scholarship in Biological Sciences, and a University of Oxford Clarendon Scholarship, which allowed me to undertake a DPhil in Cognitive Neuroscience, which I am just completing, and sub-specialist training in Cognitive Neurology.

My current research focuses on understanding the mechanisms that underlie apathy – a disorder of motivation with often debilitating consequences – in conditions including Parkinson’s disease, cerebral small vessel disease and Huntington’s disease. My work is heavily influenced by basic neuroscience developments, which I aim to translate to the clinical context. In turn, by studying patients with disorders of cognition I also aim to improve understanding of these underlying normal processes.

I have now returned to New Zealand where I work as a Neurologist specialising in Cognitive and Movement disorders. My ongoing research is centred on understanding neurobehavioural disorders and the complex neural interplay between cortical and subcortical regions that leads to the generation (or not) of actions.


Affiliations:

  • New Zealand Brain Research Institute
  • Cognitive Neurology Research Group, Nuffield Dept of Clinical Neurosciences University of Oxford, UK

Publications

Provided on request for non-commercial personal use by researchers.

2018

Download Distinct effects of apathy and dopamine on effort-based decision-making in Parkinson’s disease.
Le Heron, C., Plant, O., Manohar, S., Ang, Y. S., Jackson, M., Lennox, G., Hu, M, Husain, M. (2018). Distinct effects of apathy and dopamine on effort-based decision-making in Parkinson’s disease. Brain, 141, 1455-1469. 10.1093/brain/awy110

2017

Le Heron, C., Apps, M. A. J., Husain, M. (2017). The anatomy of apathy: a neurocognitive framework for amotivated behaviour.  Neuropsychologia. 10.1016/j.neuropsychologia.2017.07.003

2014

Hassan, I. K., Looi, J. C., Velakoulis, D., Gaillard, F., Lui, E. H., O’Brien, T. J., French, C, Le Heron, C. J., Adams, S. J. (2014). Psychosis with obsessive-compulsive symptoms in tuberous sclerosis.  Journal of Clinical Neuroscience,  21, 867-869. 10.1016/j.jocn.2013.08.005
Le Heron, C. J., Fang, K., Gubbi, J., Churilov, L., Palaniswami, M., Davis, S., Yan, B. (2014). Wireless accelerometry is feasible in acute monitoring of upper limb motor recovery after ischemic stroke. Cerebrovascular Diseases,  37, 336-341. 10.1159/000360808
Download Comparing cerebral perfusion in Alzheimer's disease and Parkinson's disease dementia: an ASL-MRI study.
Le Heron, C. J., Wright, S. L., Melzer, T. R., Myall, D. J., MacAskill, M. R., Livingston, L., Keenan, R. J., Watts, R., Dalrymple-Alford, J. C. , Anderson, T.J. (2014). Comparing cerebral perfusion in Alzheimer's disease and Parkinson's disease dementia: an ASL-MRI study.  Journal of Cerebral Blood Flow & Metabolism, 34, 964-970. 10.1038/jcbfm.2014.40

2007

Muthu, C., Chu, J. J., Le Heron, C., Roake, J. A., Lewis, D. R. (2007). Patient awareness of risk factors for peripheral vascular disease. Annals of Vascular Surgery,  21(4), 433-437. 10.1016/j.avsg.2006.06.007

2005

Download Memory-guided saccades in Parkinson's disease: long delays can improve performance.
Le Heron, C. J., MacAskill, M. R. , Anderson, T.J. (2005). Memory-guided saccades in Parkinson's disease: long delays can improve performance. Experimental Brain Research, 161, 293-298. 10.1007/s00221-004-2071-2

2004

Iles, S., Le Heron, C. J., Davies, G., Turner, J. G., Beckert, L. E. (2004). ECG score predicts those with the greatest percentage of perfusion defects due to acute pulmonary thromboembolic disease.  Chest,  125(5), 1651-1656. 10.1378/chest.125.5.1651